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Hepatic schistosomiasis with massive splenomegaly a case report and literature review

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Forgotten your password? This was further validated by findings from a liver biopsy, confirming a very rare association with Type 2 autoimmune hepatitis. It is divided into two types, associated with characteristic antibodies. Receive our free quarterly newsletters and your choice of journal publication alerts, straight to your inbox. Autoimmune hepatitis is a condition closely related to autoimmune diseases.
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VEGFA vascular endothelial growth factor A [ (human)]

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Schistosomiasis - Wikipedia

We present a report of a pregnancy complicated by chronic schistosomiasis. Physical exam was remarkable for hepatosplenomegaly. Laboratory evaluation of hepatic, renal, hematologic, autoimmune, or infectious disease etiology or abnormality was negative. Ultrasound revealed a normal fetus, an enlarged spleen, dilated splenic and hepatic vasculature and an enlarged liver with periportal fibrosis. Abdominal computed tomography revealed subcapsular calcifications, dilated ducts, and periportal fibrosis. Esophagogastrojejeunoscopy showed no varices.
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Schistosomiasis is a parasitic disease caused by Schistosoma species. Intestinal and hepatic schistosomiases are the most common forms of chronic disease. We describe a case of a year old patient from Eritrea who was referred to our hospital with abdominal pain and diarrhea. The diagnosis of hepatosplenic schistosomiasis was made by liver biopsy and the patient was treated with praziquantel.
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Malaria Journal volume 14 , Article number: Cite this article. Metrics details. The hyper-reactive malarial splenomegaly syndrome HMS is a leading cause of massive splenomegaly in malaria-endemic countries. HMS is caused by a chronic antigenic stimulation derived from the malaria parasite. The syndrome is fatal if left untreated.

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